The goal of this research is to determine whether inflammation represents a common (or distinct) mechanism for impairments in motivation across disorders of psychosis and mood. This project is poised to take advantage of a unique opportunity to build off of data collected by Dr. Deanna Barch at Washington University. Dr. Barch is recruiting a transdiagnostic sample to complete behavioral, ecological momentary assessment (EMA), and neuroimaging measures of EBDM. The TReAD Lab hopes to expand this work through the analysis of protein and genetic markers of inflammation and immunometabolism.